INT214950

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Context Info
Confidence 0.32
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.79
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
endothelial cell 2
Gbp1 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 9 98.92 Very High Very High Very High
Inflammation 9 98.52 Very High Very High Very High
Glutamate receptor 1 97.36 Very High Very High Very High
Inflammatory response 3 94.76 High High
Neurotransmitter 2 84.68 Quite High
Limbic system 1 27.52 Quite Low
Opioid 1 19.52 Low Low
interstitial cystitis 2 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
Inflammatory stimuli 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 13 98.52 Very High Very High Very High
Mycobacterial Infection 7 85.92 High High
Adhesions 2 52.08 Quite High
Infection 11 5.00 Very Low Very Low Very Low
Bladder Cancer 10 5.00 Very Low Very Low Very Low
Cancer 10 5.00 Very Low Very Low Very Low
Brain Disease 3 5.00 Very Low Very Low Very Low
Interstitial Cystitis 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Cystitis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The finding that GBP-1 expression is inhibited by potent activators of endothelial cell proliferation such as VEGF and bFGF [52], leads to the hypothesis that GTPases are in the cross-road of inflammation and vascular proliferation.
Negative_regulation (inhibited) of Gene_expression (expression) of GBP-1 in endothelial cell associated with inflammation
1) Confidence 0.32 Published 2007 Journal BMC Cancer Section Body Doc Link PMC2212656 Disease Relevance 0.74 Pain Relevance 0.27
Relatively large numbers of guanine nucleotide-binding protein (G protein) isoforms and Ras subfamily of GTPases were identified; G(s)?
Negative_regulation (numbers) of Gene_expression (isoforms) of guanine nucleotide-binding protein
2) Confidence 0.16 Published 2007 Journal Proteome Sci Section Body Doc Link PMC2045652 Disease Relevance 0.05 Pain Relevance 0.12

General Comments

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