INT215098

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Context Info
Confidence 0.18
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.18
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il6) signal transduction (Tlr4) extracellular region (Il6)
plasma membrane (Tlr4) intracellular (Tlr4) cytoplasm (Tlr4)
Tlr4 (Mus musculus)
Il6 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 13 99.28 Very High Very High Very High
Inflammatory mediators 14 95.52 Very High Very High Very High
cytokine 50 93.32 High High
Inflammatory response 18 83.84 Quite High
Inflammation 90 78.96 Quite High
agonist 8 61.16 Quite High
Kinase C 4 7.40 Low Low
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 121 95.52 Very High Very High Very High
Chlamydia Infection 24 81.12 Quite High
Disease 7 77.80 Quite High
Infection 10 73.04 Quite High
Atherosclerosis 5 63.12 Quite High
Leishmaniasis 1 61.20 Quite High
Obesity 1 50.72 Quite High
Sepsis 52 50.00 Quite Low
Bacterial Infection 3 42.24 Quite Low
Insulin Resistance 2 35.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, purified populations of endometrial cells from the WT mice secreted IL-6, CXCL1, CCL20 and PGE in response to LPS, in a dose and time dependent manner.
LPS Positive_regulation (response) of Localization (secreted) of IL-6
1) Confidence 0.18 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2943929 Disease Relevance 0.54 Pain Relevance 0.15
Furthermore, EGCG dramatically inhibited LPS-induced release of IL-6, and a number of chemokines including MIP-1?
LPS Positive_regulation (induced) of Localization (release) of IL-6 associated with chemokine
2) Confidence 0.10 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2048740 Disease Relevance 0.08 Pain Relevance 0.29
Although LPS-induced release of IL-6 was not significantly different between w.t. and PPAR??
LPS Positive_regulation (induced) of Localization (release) of IL-6
3) Confidence 0.05 Published 2008 Journal PPAR Research Section Body Doc Link PMC2443396 Disease Relevance 0.56 Pain Relevance 0.25

General Comments

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