INT215118

Context Info Confidence 0.30 First Reported 2007 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.93 Pain Relevance 0.28

extracellular space (Ighg2b)

Ighg2b (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 18 85.00 agonist 1 70.64 Inflammation 14 68.24 isoflurane 4 5.00 anesthesia 2 5.00 butorphanol 2 5.00 Analgesic 1 5.00 ketamine 1 5.00 alcohol 1 5.00 chemokine 1 5.00

Disease Link Frequency Relevance Heat Sprains And Strains 2 78.72 Immunization 26 74.64 Pox Virus Infection 2 73.84 INFLAMMATION 13 68.24 Hepatitis B Virus Infection 12 65.84 Rhinitis 1 63.68 Apoptosis 4 47.84 Infection 8 27.48 Frailty 8 26.64 Death 6 17.28

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Two-way ANOVA showed no significant effect of cathepsin D deficiency on IgM, IgG1 or IgG2b (P > 0.05).

Negative_regulation (deficiency) of IgG2b

1) Confidence 0.30 Published 2007 Journal BMC Immunol Section Body Doc Link PMC2048983 Disease Relevance 0.27 Pain Relevance 0

Prevalence of IgG2b in the overall IgG response provided additional confirmation of a Th1 bias in cellular immunity produced by HBsAg-NE vaccination.

Negative_regulation (Prevalence) of IgG2b

2) Confidence 0.22 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2496893 Disease Relevance 0.66 Pain Relevance 0.28

General Comments

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