INT215123

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Context Info
Confidence 0.44
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Ctsd) mitochondrion (Ctsd) extracellular space (Ctsd)
lysosome (Ctsd)
Anatomy Link Frequency
brain 3
liver 1
Ctsd (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Frailty 16 5.00 Very Low Very Low Very Low
Immunization 10 5.00 Very Low Very Low Very Low
Death 10 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Congenital Anomalies 8 5.00 Very Low Very Low Very Low
Weight Loss 4 5.00 Very Low Very Low Very Low
Lysosomal Storage Diseases 4 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Blindness 2 5.00 Very Low Very Low Very Low
Reprotox - General 3 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to the results obtained in liver and brain [19], LC3 protein expression in CCDWT was very low, and cathepsin D deficiency was associated with increased expression of both light (LC3II, membrane-bound) and heavy (LC3I, cytosolic) forms of LC3.
Positive_regulation (associated) of Negative_regulation (deficiency) of cathepsin D in brain
1) Confidence 0.44 Published 2007 Journal BMC Immunol Section Body Doc Link PMC2048983 Disease Relevance 0 Pain Relevance 0
In contrast to the results obtained in liver and brain [19], LC3 protein expression in CCDWT was very low, and cathepsin D deficiency was associated with increased expression of both light (LC3II, membrane-bound) and heavy (LC3I, cytosolic) forms of LC3.
Positive_regulation (associated) of in liver Negative_regulation (deficiency) of cathepsin D in brain
2) Confidence 0.15 Published 2007 Journal BMC Immunol Section Body Doc Link PMC2048983 Disease Relevance 0 Pain Relevance 0

General Comments

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