INT215222

Context Info Confidence 0.74 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.46 Pain Relevance 0

Golgi apparatus (Rab27b) plasma membrane (Rab27b) GTPase activity (Rab27b) cytoplasm (Rab27b)

Anatomy Link Frequency mast cell 1 Rab27b (Mus musculus)

Pain Link Frequency Relevance Heat imagery 4 15.12 Serotonin 6 5.00 Inflammatory mediators 2 5.00 cytokine 1 5.00 anesthesia 1 5.00

Disease Link Frequency Relevance Heat Targeted Disruption 49 87.92 Syndrome 2 75.52 Leukemia 1 20.00 Anaphylaxis 10 5.00 Hypersensitivity 6 5.00 Sprains And Strains 3 5.00 Disease 2 5.00 INFLAMMATION 2 5.00 Asthma 2 5.00 Exsanguination 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

One surprising result obtained here was the increased secretory responses in BMMCs derived from Rab27aash/ash mice, raising the possibility that Rab27a and Rab27b might have distinct roles in mast cell secretion.

Localization (secretion) of Rab27b in mast cell

1) Confidence 0.74 Published 2007 Journal Traffic (Copenhagen, Denmark) Section Body Doc Link PMC2063611 Disease Relevance 0.46 Pain Relevance 0

General Comments

This test has worked.