INT215223

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Context Info
Confidence 0.45
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.73
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Rab27a) Golgi apparatus (Rab27a) intracellular (Rab27a)
GTPase activity (Rab27a) pigmentation (Rab27a) vesicle-mediated transport (Rab27a)
Anatomy Link Frequency
melanocytes 3
hematopoietic cells 1
Rab27a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory mediators 4 36.96 Quite Low
Serotonin 12 30.92 Quite Low
imagery 8 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Immunodeficiency 2 86.48 High High
Piebaldism 2 83.80 Quite High
Syndrome 4 81.72 Quite High
Targeted Disruption 98 56.16 Quite High
Asthma 4 44.24 Quite Low
Disease 4 43.60 Quite Low
Hypersensitivity 12 43.24 Quite Low
INFLAMMATION 4 36.56 Quite Low
Anaphylaxis 20 5.00 Very Low Very Low Very Low
Sprains And Strains 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present evidence thus suggests that Rab27a acts as a positive regulator of regulated secretion in either conventional Golgi-derived granules in exocrine and endocrine cells, or lysosome-related organelles in hematopoietic cells and melanocytes (19,21,24).
Regulation (regulated) of Localization (secretion) of Rab27a in melanocytes
1) Confidence 0.45 Published 2007 Journal Traffic (Copenhagen, Denmark) Section Body Doc Link PMC2063611 Disease Relevance 0.36 Pain Relevance 0
The present evidence thus suggests that Rab27a acts as a positive regulator of regulated secretion in either conventional Golgi-derived granules in exocrine and endocrine cells, or lysosome-related organelles in hematopoietic cells and melanocytes (19,21,24).
Regulation (regulated) of in hematopoietic cells Localization (secretion) of Rab27a in melanocytes
2) Confidence 0.15 Published 2007 Journal Traffic (Copenhagen, Denmark) Section Body Doc Link PMC2063611 Disease Relevance 0.36 Pain Relevance 0

General Comments

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