INT215224

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Rab27b) plasma membrane (Rab27b) GTPase activity (Rab27b)
cytoplasm (Rab27b)
Anatomy Link Frequency
mast cell 1
Rab27b (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 6 53.52 Quite High
imagery 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypersensitivity 6 99.80 Very High Very High Very High
Disease 2 99.44 Very High Very High Very High
Asthma 2 98.72 Very High Very High Very High
Targeted Disruption 49 97.96 Very High Very High Very High
Leukemia 1 76.84 Quite High
Syndrome 2 9.84 Low Low
Anaphylaxis 10 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Exsanguination 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The identification of severely reduced mast cell responses in vivo in the Rab27b KO mouse is the first report that Rab27b contributes to allergic responses in mammals and suggests that Rab27b may be a future drug target for allergic diseases, such as asthma.
Regulation (target) of Rab27b in mast cell associated with asthma, targeted disruption, hypersensitivity and disease
1) Confidence 0.27 Published 2007 Journal Traffic (Copenhagen, Denmark) Section Body Doc Link PMC2063611 Disease Relevance 0.65 Pain Relevance 0.03

General Comments

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