INT215270

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.38
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ncf1, Ncf4) cytoplasm (Ncf1, Ncf4) cell proliferation (Ncf1)
Golgi apparatus (Ncf1) plasma membrane (Ncf1)
Anatomy Link Frequency
plasma 1
Ncf1 (Mus musculus)
Ncf4 (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 1 75.60 Quite High
Inflammatory response 2 65.40 Quite High
Inflammation 31 59.20 Quite High
Inflammatory mediators 7 21.96 Low Low
midbrain 4 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
opioid receptor 2 5.00 Very Low Very Low Very Low
narcan 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
opiate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 17 69.92 Quite High
INFLAMMATION 40 65.00 Quite High
Drug Induced Neurotoxicity 22 64.80 Quite High
Toxicity 6 35.84 Quite Low
Death 6 5.00 Very Low Very Low Very Low
Parkinson's Disease 4 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 4 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As the activation of a functional PHOX enzyme requires the phorsphorylation of p47phox followed by the translocation of the p47phox, p67phox, and p40phox complex to the plasma membrane, our results suggest that SN works on one of the earliest stages of PHOX activation to inhibit the assembly of the PHOX enzyme complex.
p47phox Binding (complex) of p40phox in plasma
1) Confidence 0.05 Published 2007 Journal J Neuroinflammation Section Body Doc Link PMC2064906 Disease Relevance 0.38 Pain Relevance 0.17

General Comments

This test has worked.

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