INT215274

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.02
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.48
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4, Ros1) plasma membrane (Tlr4, Ros1) cell differentiation (Ros1)
cell proliferation (Ros1) intracellular (Tlr4) kinase activity (Ros1)
Anatomy Link Frequency
microglia 1
Tlr4 (Mus musculus)
Ros1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 45 97.24 Very High Very High Very High
Inflammatory mediators 8 94.80 High High
Paracetamol 1 60.04 Quite High
Potency 1 20.16 Low Low
Inflammatory response 9 5.00 Very Low Very Low Very Low
midbrain 4 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
opioid receptor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemorrhagic Shock 32 99.84 Very High Very High Very High
Drug Induced Neurotoxicity 22 98.12 Very High Very High Very High
INFLAMMATION 55 97.24 Very High Very High Very High
Adult Respiratory Distress Syndrome 27 96.88 Very High Very High Very High
Injury 18 83.88 Quite High
Toxicity 7 60.40 Quite High
Stress 6 36.24 Quite Low
Disease 18 5.00 Very Low Very Low Very Low
Death 9 5.00 Very Low Very Low Very Low
Shock 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent studies have further demonstrated that ROS are important determinants for augmented TLR4-induced TLR2 upregulation in HS.
TLR4 Spec (determinants) Positive_regulation (upregulation) of ROS associated with hemorrhagic shock
1) Confidence 0.02 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2913855 Disease Relevance 0.93 Pain Relevance 0.10
We first tested the effect of SN on the LPS-induced ROS generation, including extracellular superoxide and intracellular ROS in microglia-enriched cultures.
LPS Positive_regulation (induced) of ROS in microglia
2) Confidence 0.00 Published 2007 Journal J Neuroinflammation Section Body Doc Link PMC2064906 Disease Relevance 0.55 Pain Relevance 0.18

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox