INT2153

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Context Info
Confidence 0.42
First Reported 1979
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 9
Total Number 10
Disease Relevance 1.14
Pain Relevance 1.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Oxt) extracellular region (Oxt) cytoplasm (Oxt)
Anatomy Link Frequency
plasma 4
P19 2
CSF 2
heart 2
PGE2 2
Oxt (Mus musculus)
Pain Link Frequency Relevance Heat
epidural 4 100.00 Very High Very High Very High
analgesia 4 100.00 Very High Very High Very High
antagonist 32 99.26 Very High Very High Very High
cINOD 1 93.20 High High
Opioid 5 91.20 High High
Intracerebroventricular 4 85.24 High High
anesthesia 4 84.24 Quite High
Buprenorphine 1 76.32 Quite High
Dismenorea 3 52.32 Quite High
Inflammation 2 14.32 Low Low
Disease Link Frequency Relevance Heat
Embryonal Carcinoma 46 99.68 Very High Very High Very High
INFLAMMATION 3 93.00 High High
Reprotox - General 1 1 92.80 High High
Disease 1 91.16 High High
Ulcers 1 90.84 High High
Nociception 1 88.72 High High
Dystocia 2 75.00 Quite High
Stress 1 75.00 Quite High
Congenital Anomalies 1 68.24 Quite High
Pressure Volume 2 Under Development 1 62.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Geometric incrementation should be limited to nulliparas in whom each dose of oxytocin is evaluated after a 40-minute infusion period.
Negative_regulation (evaluated) of Positive_regulation (dose) of oxytocin
1) Confidence 0.42 Published 1987 Journal Clin Obstet Gynecol Section Abstract Doc Link 3581558 Disease Relevance 0.13 Pain Relevance 0.05
The use of oxytocin augmentation is reduced when intravaginal misoprostol is used compared with other agents.
Negative_regulation (reduced) of Positive_regulation (augmentation) of oxytocin
2) Confidence 0.42 Published 2002 Journal Drug Saf Section Abstract Doc Link 12137560 Disease Relevance 0.34 Pain Relevance 0.09
Coadministration of phenylephrine obtunded oxytocin-induced decreases in systemic vascular resistance and increases in heart rate and CO.
Negative_regulation (decreases) of Positive_regulation (increases) of oxytocin in heart
3) Confidence 0.36 Published 2009 Journal Anesthesiology Section Body Doc Link 19741494 Disease Relevance 0.06 Pain Relevance 0
Similarly, the plasma OT-X elevation reported during early fetal development in sheep [3] is reduced in late gestation, when OT begins to predominate in the circulation.
Negative_regulation (reduced) of Positive_regulation (elevation) of OT in plasma
4) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2964328 Disease Relevance 0.05 Pain Relevance 0
We observed that both V1aR antagonist as well as V1aR silencing partially blocked the cardiomyogenic effects of OT-GKR in EC P19 cells.
Negative_regulation (blocked) of Positive_regulation (effects) of OT in P19 associated with antagonist and embryonal carcinoma
5) Confidence 0.30 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2964328 Disease Relevance 0.30 Pain Relevance 0.14
Subacute M320 treatment did not inhibit this elevated OXY release.
Negative_regulation (inhibit) of Positive_regulation (elevated) of OXY
6) Confidence 0.20 Published 1989 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 2721029 Disease Relevance 0 Pain Relevance 0.29
Phentolamine did not prevent either CSF or plasma increases in oxytocin, following vaginocervical stimulation, but reduced basal plasma levels.
Negative_regulation (prevent) of Positive_regulation (increases) of oxytocin in plasma
7) Confidence 0.15 Published 1989 Journal Brain Res. Section Abstract Doc Link 2598052 Disease Relevance 0 Pain Relevance 0.17
Naltrexone also prevented the CSF increase in oxytocin following vaginocervical stimulation but was without effect on plasma levels.
Negative_regulation (prevented) of Positive_regulation (increase) of oxytocin in CSF
8) Confidence 0.13 Published 1989 Journal Brain Res. Section Abstract Doc Link 2598052 Disease Relevance 0 Pain Relevance 0.16
The responses of oxytocin (OXT) and prolactin (PRL) were more susceptible to epidural analgesia and were blocked at the C8-T2 level.
Negative_regulation (blocked) of Positive_regulation (responses) of oxytocin associated with epidural and analgesia
9) Confidence 0.06 Published 1996 Journal Anesth. Analg. Section Abstract Doc Link 8638794 Disease Relevance 0.16 Pain Relevance 0.52
While the numbers of patients requiring oxytocin stimulation of labour and regional analgesia were reduced in both groups compared with the controls, PGF2 alpha was much less effective than PGE2.
Negative_regulation (reduced) of Positive_regulation (requiring) of oxytocin in PGE2 associated with analgesia
10) Confidence 0.03 Published 1979 Journal Br J Obstet Gynaecol Section Abstract Doc Link 371664 Disease Relevance 0.09 Pain Relevance 0.10

General Comments

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