INT215301

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Context Info
Confidence 0.27
First Reported 2007
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 9
Total Number 10
Disease Relevance 10.36
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (PQBP1) nucleus (PQBP1) DNA binding (PQBP1)
cytoplasm (PQBP1)
Anatomy Link Frequency
middle ear 1
respiratory tract 1
Shoulder 1
articular 1
lower respiratory tract 1
PQBP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
reflex sympathetic dystrophy 3 100.00 Very High Very High Very High
Rsd 6 97.44 Very High Very High Very High
Pain 8 89.28 High High
Inflammation 15 88.96 High High
visual analogue scale 4 67.88 Quite High
alcohol 8 32.88 Quite Low
depression 1 25.92 Quite Low
Osteoarthritis 1 10.72 Low Low
cINOD 2 5.52 Low Low
rheumatoid arthritis 31 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 19 100.00 Very High Very High Very High
Obesity 7 100.00 Very High Very High Very High
Nicotine Addiction 248 99.96 Very High Very High Very High
Complex Regional Pain Syndromes 5 99.96 Very High Very High Very High
Infection 66 99.32 Very High Very High Very High
Respiratory Disease 40 99.12 Very High Very High Very High
Disease 151 99.00 Very High Very High Very High
Asthma 136 99.00 Very High Very High Very High
Lung Cancer 18 98.92 Very High Very High Very High
Emphysema 8 98.80 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Among lifetime nonsmokers, SHS is also associated with an increased risk of lung cancer and death and disability from coronary heart disease (CHD).
SHS Binding (associated) of in lung associated with coronary artery disease, lung cancer and death
1) Confidence 0.27 Published 2007 Journal Environ Health Section Body Doc Link PMC2064907 Disease Relevance 1.28 Pain Relevance 0
The letter informed members of the cohort that this study would examine the association between SHS and adverse health outcomes but not specifically about respiratory tract diseases.
SHS Neg (not) Spec (examine) Binding (association) of in respiratory tract associated with respiratory disease
2) Confidence 0.27 Published 2007 Journal Environ Health Section Body Doc Link PMC2064907 Disease Relevance 0.10 Pain Relevance 0
SHS has been observed to be independently, positively associated with respiratory tract symptoms such as sneezing, sore throat, and cough [7] as well as nasal rhinitis [8].
SHS Binding (associated) of in nasal associated with rhinitis, pharyngitis, cough and sneezing
3) Confidence 0.23 Published 2007 Journal Environ Health Section Body Doc Link PMC2064907 Disease Relevance 1.50 Pain Relevance 0.03
In healthy adults, SHS is associated with upper and lower respiratory tract diseases and an increased risk of asthma and chronic obstructive pulmonary disease (i.e., bronchitis and emphysema).
SHS Binding (associated) of in lower respiratory tract associated with asthma, emphysema, pulmonary disease, bronchitis and respiratory disease
4) Confidence 0.20 Published 2007 Journal Environ Health Section Body Doc Link PMC2064907 Disease Relevance 1.13 Pain Relevance 0
In a prospective study of 3914 adult non smokers, SHS was significantly associated with the development of asthma over a 10-year period [relative risk (RR) = 1.45; 95% CI: 1.21–1.75] [17].
SHS Binding (associated) of associated with asthma and nicotine addiction
5) Confidence 0.20 Published 2007 Journal Environ Health Section Body Doc Link PMC2064907 Disease Relevance 1.09 Pain Relevance 0
In a cross-sectional study of 4197 never smoking adults in Switzerland, SHS was significantly associated with physician-diagnosed asthma (OR 1.39; 95% CI: 1.04–1.86) [13].
SHS Binding (associated) of associated with asthma and nicotine addiction
6) Confidence 0.20 Published 2007 Journal Environ Health Section Body Doc Link PMC2064907 Disease Relevance 1.31 Pain Relevance 0.03
The association of SHS exposure and sinusitis has not been extensively studied in adults and most of the evidence concerning the association of SHS with middle ear infections comes from the pediatric literature [1].
SHS Binding (association) of in middle ear associated with sinusitis and infection
7) Confidence 0.20 Published 2007 Journal Environ Health Section Body Doc Link PMC2064907 Disease Relevance 1.40 Pain Relevance 0.04
Shoulder-hand syndrome (SHS) is a relatively rare clinical entity classified as a complex regional pain syndrome type 1 (CRPS1), indicated previously as reflex sympathetic dystrophy (RSD) [1].
SHS Binding (complex) of in Shoulder associated with complex regional pain syndromes, rsd, reflex sympathetic dystrophy and syndrome
8) Confidence 0.18 Published 2008 Journal J Med Case Reports Section Body Doc Link PMC2516525 Disease Relevance 0.94 Pain Relevance 0.38
In healthy adults, SHS is associated with upper and lower respiratory tract diseases and an increased risk of asthma and chronic obstructive pulmonary disease (i.e., bronchitis and emphysema).
SHS Binding (associated) of in upper associated with asthma, emphysema, pulmonary disease, bronchitis and respiratory disease
9) Confidence 0.07 Published 2007 Journal Environ Health Section Body Doc Link PMC2064907 Disease Relevance 1.13 Pain Relevance 0
To determine the associations between hand BMD loss and progressive joint damage in hands and feet after one year, multivariate logistic regression analyses were performed adjusted for age, gender, postmenopausal status, BMI, HAQ, baseline SHS, treatment group, and the use of intra-articular steroids and antiresorptive drugs (bisphosphonates, vitamin D and calcium supplements and hormone replacement therapy (HRT)).
SHS Binding (age) of in articular associated with obesity
10) Confidence 0.02 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0.50 Pain Relevance 0.10

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