INT215302

Context Info Confidence 0.53 First Reported 2007 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 15 Total Number 15 Disease Relevance 3.93 Pain Relevance 0.31

nucleolus (PQBP1) nucleus (PQBP1) DNA binding (PQBP1) cytoplasm (PQBP1)

Anatomy Link Frequency joint 2 superior 1 PQBP1 (Homo sapiens)

Pain Link Frequency Relevance Heat visual analogue scale 41 90.88 rheumatoid arthritis 310 87.92 Inflammation 93 75.72 Crohn's disease 20 61.24 corticosteroid 46 39.28 alcohol 3 26.72 Infliximab 13 23.80 headache 6 9.96 methotrexate 70 5.00 Arthritis 20 5.00

Disease Link Frequency Relevance Heat Disease 292 99.80 Nicotine Addiction 94 99.32 Inflammatory Bowel Disease 51 98.08 Femoral Neck Fractures 59 92.08 Rheumatoid Arthritis 310 87.92 Cadaver 1 87.84 Fatigue 8 82.96 INFLAMMATION 99 75.72 Coronary Artery Disease 9 66.92 Lung Cancer 6 66.60

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Moreover, they found that a derotation screw located superior to the SHS did not add any increase in fixation after the SHS is placed.

Gene_expression (placed) of SHS in superior

1) Confidence 0.53 Published 2008 Journal Indian Journal of Orthopaedics Section Body Doc Link PMC2759588 Disease Relevance 0.60 Pain Relevance 0

However, under the assumption that this response bias was independent of SHS exposure, the findings from the analyses assessing the association between SHS exposure and disease would not be affected.

Gene_expression (exposure) of SHS associated with disease

2) Confidence 0.43 Published 2007 Journal Environ Health Section Body Doc Link PMC2064907 Disease Relevance 0.40 Pain Relevance 0

However, under the assumption that this response bias was independent of SHS exposure, the findings from the analyses assessing the association between SHS exposure and disease would not be affected.

Gene_expression (exposure) of SHS associated with disease

3) Confidence 0.38 Published 2007 Journal Environ Health Section Body Doc Link PMC2064907 Disease Relevance 0.35 Pain Relevance 0

Less is known about the potential long-term health consequences experienced by FAs exposed to SHS during the time smoking was allowed on airplanes.

Gene_expression (exposed) of SHS associated with nicotine addiction

4) Confidence 0.38 Published 2007 Journal Environ Health Section Body Doc Link PMC2064907 Disease Relevance 1.15 Pain Relevance 0

The mean (SD) progression of total SHS was 2.9 (7.6) after four years compared with year one and 14% of the patients had progressive total joint damage of 5 units or more after four years compared with year one.

Gene_expression (progression) of SHS in joint

5) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0 Pain Relevance 0

The mean (SD) cumulative progression of total SHS in hands and feet was 3.0 (11.3), 4.9 (14.5), 5.8 (16.7) and 6.6 (13.3) after one to four years compared with baseline.

Gene_expression (progression) of SHS

6) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0 Pain Relevance 0

The mean (SD) progression of total SHS in hands and feet, and SHS in hands and feet separately was 3.0 (11.3), 1.9 (7.0) and 1.1 (5.0), respectively.

Gene_expression (progression) of SHS

7) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0.05 Pain Relevance 0

The mean (SD) progression of total SHS in hands and feet, and SHS in hands and feet separately was 3.0 (11.3), 1.9 (7.0) and 1.1 (5.0), respectively.

Gene_expression (progression) of SHS

8) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0.05 Pain Relevance 0

To explore further the usefulness of progressive joint damage in the first year as a predictor of subsequent progressive damage, joint damage progression in the first year was divided in to four groups: no progression (SHS ?

Neg (no) Gene_expression (progression) of SHS in joint

9) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0.06 Pain Relevance 0.03

0 unit, the reference group), dubious progression (0<SHS<5 units), moderate progression (5 ?

Gene_expression (progression) of SHS

10) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0.06 Pain Relevance 0.03

SHS<10 units) and high progression (SHS ?

Gene_expression (progression) of SHS

11) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0.06 Pain Relevance 0.03

It might be argued whether progression of SHS is useful in clinical practice as a predictor, because it is a complicated scoring method that requires special training to perform.

Gene_expression (progression) of SHS

12) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0.41 Pain Relevance 0.11

In patients with hand BMD loss the mean (SD) progression of total SHS after one year was 4.0 (13.6) compared with 1.1 (2.6) in patients without hand BMD loss (P = 0.036 derived by non-parametric test).

Gene_expression (progression) of SHS

13) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0 Pain Relevance 0

SHS<10 units) and high progression (SHS ?

Gene_expression (progression) of SHS

14) Confidence 0.04 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2911882 Disease Relevance 0.06 Pain Relevance 0.03

The levels of SHS sub-scales and the scores according to HBI and UC-DAI are shown in box plots, one box per time point measured.

Gene_expression (levels) of SHS associated with inflammatory bowel disease

15) Confidence 0.02 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2914086 Disease Relevance 0.68 Pain Relevance 0.08

General Comments

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