INT215348

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.43
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (VDAC1) plasma membrane (VDAC1) transmembrane transport (VDAC1)
VDAC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fluoxetine 6 99.62 Very High Very High Very High
addiction 9 98.72 Very High Very High Very High
Disease Link Frequency Relevance Heat
Apoptosis 45 96.68 Very High Very High Very High
Targeted Disruption 3 67.60 Quite High
Death 33 61.48 Quite High
Disease 15 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 15 5.00 Very Low Very Low Very Low
Neuroblastoma 3 5.00 Very Low Very Low Very Low
Dementia 3 5.00 Very Low Very Low Very Low
Spinocerebellar Ataxia Type 2 3 5.00 Very Low Very Low Very Low
Tremor 3 5.00 Very Low Very Low Very Low
Stroke 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
VDAC can associate with small ions, control the passage of key adenine nucleotides, interact with other proteins like cellular kinases and regulate mitochondrial permeability [17], [19].
VDAC Binding (interact) of
1) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2064964 Disease Relevance 0.62 Pain Relevance 0
VDAC can associate with small ions, control the passage of key adenine nucleotides, interact with other proteins like cellular kinases and regulate mitochondrial permeability [17], [19].
VDAC Binding (associate) of
2) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2064964 Disease Relevance 0.55 Pain Relevance 0
Fluoxetine has been shown to interact with the VDAC channel and modify its voltage dependence and conductance and in certain cell types can provide protection from apoptosis [25].
VDAC Binding (interact) of associated with addiction, apoptosis and fluoxetine
3) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2064964 Disease Relevance 0.26 Pain Relevance 0.33

General Comments

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