INT215470

Context Info Confidence 0.05 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.94 Pain Relevance 0

nucleus (CRAMP1L) plasma membrane (HLA-B) DNA binding (CRAMP1L)

HLA-B (Homo sapiens) CRAMP1L (Homo sapiens)

Pain Link Frequency Relevance Heat carbamazepine 2 42.16 spinal inflammation 1 5.00

Disease Link Frequency Relevance Heat Hypersensitivity 31 100.00 Eczema 30 100.00 Syndrome 8 98.68 Acquired Immune Deficiency Syndrome Or Hiv Infection 1 65.84 Genetic Predisposition To Disease 1 50.00 Adverse Drug Reaction 1 28.08 Disease 10 5.00 Staphylococcus Infection 5 5.00 Fever 4 5.00 Autoimmune Disease 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In a previous study that included 15 white patients, Mondino et al. (1982) found that HLA-B*44 was associated with the risk of Stevens-Johnson syndrome with ocular involvement; therefore, it is possible that the weak association of HLA-B*44 with hypersensitivity dermatitis in TCE-exposed workers is not a chance finding.

HLA-B Binding (association) of TCE associated with syndrome, hypersensitivity and eczema

1) Confidence 0.05 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC2072824 Disease Relevance 0.94 Pain Relevance 0

General Comments

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