INT215514

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.48
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Lpar6) signal transducer activity (Lpar6)
Anatomy Link Frequency
glial cells 1
Lpar6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 30 99.96 Very High Very High Very High
adenocard 94 91.44 High High
antagonist 32 87.80 High High
Glutamate 73 70.40 Quite High
Central nervous system 13 70.20 Quite High
Glutamate receptor 6 13.64 Low Low
ischemia 13 5.00 Very Low Very Low Very Low
Hippocampus 13 5.00 Very Low Very Low Very Low
Neurotransmitter 12 5.00 Very Low Very Low Very Low
tetrodotoxin 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 11 99.66 Very High Very High Very High
Pressure And Volume Under Development 52 88.64 High High
Ganglion Cysts 20 81.76 Quite High
Targeted Disruption 15 73.60 Quite High
Embryonal Carcinoma 7 57.04 Quite High
Stress 18 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 13 5.00 Very Low Very Low Very Low
Retina Disease 10 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 10 5.00 Very Low Very Low Very Low
Hypoxia 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The discovery of such selective compounds will elucidate yet unknown biological functions of P2 receptor subtypes as well as open new avenues for therapeutic approaches to disease states in which purinergic receptor activity is involved.



Regulation (involved) of purinergic receptor associated with disease
1) Confidence 0.01 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072925 Disease Relevance 0.23 Pain Relevance 0.15
The activity of ectonucleotidases controls the level of purinergic receptor agonists in the extracellular space.
Regulation (controls) of purinergic receptor associated with agonist
2) Confidence 0.01 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072913 Disease Relevance 0.09 Pain Relevance 0.29
It is concluded that the activity of ectonucleotidases regulates the purinergic receptor-mediated calcium responses in Müller glial cells.
Regulation (regulates) of purinergic receptor in glial cells
3) Confidence 0.01 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072913 Disease Relevance 0.16 Pain Relevance 0.11

General Comments

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