INT215564

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Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (P2ry2) aging (P2ry2) embryo development (P2ry2)
signal transducer activity (P2ry2) cell-cell signaling (Hmmr) cytoplasm (Hmmr)
Hmmr (Rattus norvegicus)
P2ry2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
noradrenaline 10 99.84 Very High Very High Very High
Central nervous system 17 77.44 Quite High
Hippocampus 11 68.96 Quite High
Serotonin 5 57.60 Quite High
Dopamine 10 56.00 Quite High
excitatory amino acid 3 51.12 Quite High
Peripheral nervous system 9 51.00 Quite High
monoamine 3 50.04 Quite High
Neurotransmitter 23 50.00 Quite Low
Glutamate 22 49.20 Quite Low
Disease Link Frequency Relevance Heat
Bordatella Infection 1 20.48 Low Low
Targeted Disruption 5 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 5 5.00 Very Low Very Low Very Low
Ganglion Cysts 4 5.00 Very Low Very Low Very Low
Coronary Heart Disease 3 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Arrhythmia Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mechanism of P2Y receptor-mediated inhibition of noradrenaline release has also been explored in several studies: the activation of P2Y receptors inhibits voltage-dependent Ca2+ influx and thereby limits the Ca2+-dependent vesicular exocytosis and subsequent efflux of noradrenaline to the extracellular space [189, 193, 194].
receptor-mediated Negative_regulation (inhibition) of P2Y associated with noradrenaline
1) Confidence 0.00 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072919 Disease Relevance 0 Pain Relevance 0.44

General Comments

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