INT215565

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.18
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc35a3) Golgi apparatus (Slc35a3) plasma membrane (P2ry14)
signal transducer activity (P2ry14)
Slc35a3 (Rattus norvegicus)
P2ry14 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
adenocard 17 58.00 Quite High
agonist 6 53.12 Quite High
Neurotransmitter 23 50.00 Quite Low
Spinal cord 7 42.12 Quite Low
Hippocampus 11 41.28 Quite Low
medulla 6 40.76 Quite Low
Neuronal excitability 1 26.72 Quite Low
Thalamus 1 18.40 Low Low
cerebral cortex 3 17.48 Low Low
Glutamate 22 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 5 67.24 Quite High
Cv Unclassified Under Development 5 5.00 Very Low Very Low Very Low
Ganglion Cysts 4 5.00 Very Low Very Low Very Low
Coronary Heart Disease 3 5.00 Very Low Very Low Very Low
Hypoxia 2 5.00 Very Low Very Low Very Low
Depression 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Neurological Disease 2 5.00 Very Low Very Low Very Low
Arrhythmia Under Development 2 5.00 Very Low Very Low Very Low
Coronary Artery Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
P2Y receptors are basically activated by adenine and uridine nucleotides, such as ATP, ADP, uridine diphosphate (UDP), and uridine triphosphate (UTP), but not by nucleosides and they are classified according to their sensitivity to purines and/or pyrimidines: P2Y1, 12 and P2Y13 are adenine nucleotide-preferring receptors; P2Y6 is preferred by uridine nucleotides; P2Y2, 4 and P2Y11 are receptors with mixed selectivity; whereas P2Y14 is activated by UDP-glucose, UDP-galactose, UDP-N-acetylglucosamine, and UDP-glucuronic acid [83].
UDP-N-acetylglucosamine Positive_regulation (activated) of P2Y14
1) Confidence 0.01 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072919 Disease Relevance 0.18 Pain Relevance 0.06

General Comments

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