INT215646

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.51
Pain Relevance 0.85

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Adora1, P2rx2) signal transduction (Adora1) endoplasmic reticulum (Adora1)
signal transducer activity (Adora1)
Anatomy Link Frequency
neurons 1
Adora1 (Mus musculus)
P2rx2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
adenocard 184 97.20 Very High Very High Very High
nMDA receptor 12 91.20 High High
Glutamate 28 90.00 High High
Calcium channel 4 89.32 High High
Neurotransmitter 6 87.28 High High
antagonist 36 85.88 High High
agonist 54 85.24 High High
Central nervous system 20 84.56 Quite High
Glutamate receptor 4 74.64 Quite High
Serotonin 4 70.64 Quite High
Disease Link Frequency Relevance Heat
Ataxia 4 98.20 Very High Very High Very High
Hypoxia 16 73.76 Quite High
Drug Induced Neurotoxicity 4 63.52 Quite High
Cv Unclassified Under Development 2 56.32 Quite High
Apoptosis 2 29.12 Quite Low
Necrosis 2 28.00 Quite Low
Disease 12 5.00 Very Low Very Low Very Low
Neurological Disease 10 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Bordatella Infection 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Functional interaction between A1Rs and P2X receptors
A1R Binding (interaction) of P2X
1) Confidence 0.13 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072922 Disease Relevance 0.44 Pain Relevance 0.29
In addition to its direct presynaptic and postsynaptic actions on neurons, A1R interaction with NMDA [80–82, 84], GABAA [85–88], and P2X receptors [80, 89–91] contributes to fine-tuning neuromodulation via adenosine.
A1R Binding (interaction) of P2X in neurons associated with adenocard
2) Confidence 0.03 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072922 Disease Relevance 0.06 Pain Relevance 0.57

General Comments

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