INT21576

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Context Info
Confidence 0.03
First Reported 1990
Last Reported 1990
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NT5C3) mitochondrion (NT5C3) aging (TIMP1)
extracellular region (TIMP1) small molecule metabolic process (NT5C3) endoplasmic reticulum (NT5C3)
Anatomy Link Frequency
PGE2 2
NT5C3 (Homo sapiens)
TIMP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 3 97.40 Very High Very High Very High
cINOD 1 77.96 Quite High
Disease Link Frequency Relevance Heat
INFLAMMATION 4 97.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CN-100 did not inhibited directly the collagenase production, but significantly prevent the biosynthesis of PGE2 known as an inflammatory mediator.
CN-100 Negative_regulation (inhibited) of Gene_expression (production) of collagenase in PGE2 associated with inflammation
1) Confidence 0.03 Published 1990 Journal Res. Commun. Chem. Pathol. Pharmacol. Section Abstract Doc Link 2177561 Disease Relevance 0.25 Pain Relevance 0.20

General Comments

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