INT215783

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Context Info
Confidence 0.12
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.64
Pain Relevance 0.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gnas) endosome (Gnas) signal transduction (Gnas)
extracellular region (Gnas) plasma membrane (Gnas) GTPase activity (Gnas)
Gnas (Mus musculus)
Pain Link Frequency Relevance Heat
Nucleus accumbens 66 98.96 Very High Very High Very High
antagonist 33 92.68 High High
agonist 60 77.52 Quite High
Spinal cord 3 74.56 Quite High
Multiple sclerosis 3 72.20 Quite High
ischemia 6 70.44 Quite High
cytokine 6 54.36 Quite High
Inflammation 9 53.96 Quite High
Brush evoked pain 3 34.48 Quite Low
imagery 3 20.08 Low Low
Disease Link Frequency Relevance Heat
Injury 129 99.44 Very High Very High Very High
Apoptosis 48 95.48 Very High Very High Very High
Proliferative Vitreoretinopathy 3 81.96 Quite High
Disease 3 79.60 Quite High
Amyloid Plaque 3 78.00 Quite High
Motor Neuron Diseases 3 73.56 Quite High
Demyelinating Disease 3 72.20 Quite High
Cv Unclassified Under Development 6 70.44 Quite High
INFLAMMATION 12 53.96 Quite High
Nervous System Injury 6 35.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data also demonstrate a strong colocalization of the P2Y6 receptor with GSA-IR.
Localization (colocalization) of GSA
1) Confidence 0.12 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072928 Disease Relevance 0.66 Pain Relevance 0.20
However, no colocalization of pAkt with GSA-B4-positive cells (Fig. 3i,j) was found by immunofluorescence labeling.
Localization (colocalization) of GSA
2) Confidence 0.12 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072928 Disease Relevance 0.45 Pain Relevance 0.25
Double immunofluorescence-labeling showed colocalization of active caspase 3 at single GSA-B4-positive cells in the NAc of rats (Fig. 3e,f).
Localization (colocalization) of GSA associated with nucleus accumbens
3) Confidence 0.10 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072928 Disease Relevance 0.53 Pain Relevance 0.31

General Comments

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