INT215788

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.84
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (P2rx6)
P2rx6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 71 94.40 High High
agonist 23 76.80 Quite High
Spinal cord 5 74.56 Quite High
Multiple sclerosis 2 72.20 Quite High
ischemia 19 70.44 Quite High
cytokine 5 54.36 Quite High
Inflammation 9 53.96 Quite High
Sciatic nerve 15 43.84 Quite Low
antagonist 16 41.84 Quite Low
unmyelinated 1 39.52 Quite Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 72 94.40 High High
Injury 50 90.96 High High
Proliferative Vitreoretinopathy 1 81.96 Quite High
Toxicity 1 80.44 Quite High
Disease 6 79.60 Quite High
Amyloid Plaque 1 78.00 Quite High
Neuropathic Pain 20 75.36 Quite High
Nerve Compression Syndromes 45 74.16 Quite High
Motor Neuron Diseases 1 73.56 Quite High
Demyelinating Disease 2 72.20 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of all the P2X subunits, only P2X6 and P2X7 colocalized with DCX in the SVZ (Tab. 2).
Localization (colocalized) of P2X6
1) Confidence 0.42 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2669296 Disease Relevance 0.19 Pain Relevance 0.03
Our data also demonstrate a strong colocalization of the P2Y6 receptor with GSA-IR.
Localization (colocalization) of P2Y6 receptor
2) Confidence 0.20 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2072928 Disease Relevance 0.66 Pain Relevance 0.20
At this extracellular [ATP], some degree of P2X3 receptor desensitization would be expected [40,41].
Localization (desensitization) of P2X3 receptor
3) Confidence 0.05 Published 2008 Journal Mol Pain Section Body Doc Link PMC2630978 Disease Relevance 0.99 Pain Relevance 0.36

General Comments

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