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Context Info
Confidence 0.24
First Reported 1990
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 9
Total Number 9
Disease Relevance 4.21
Pain Relevance 1.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (IL4I1) lysosome (IL4I1)
Anatomy Link Frequency
synovial cells 1
temporomandibular joint 1
fibroblasts 1
stem cell 1
pole 1
IL4I1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 24 100.00 Very High Very High Very High
antagonist 5 99.84 Very High Very High Very High
Snapping jaw 2 99.56 Very High Very High Very High
agonist 32 98.16 Very High Very High Very High
Arthritis 1 93.88 High High
Pain 2 91.76 High High
cINOD 1 84.20 Quite High
Inflammation 6 80.24 Quite High
addiction 22 49.48 Quite Low
methadone 28 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mental Disorders 268 100.00 Very High Very High Very High
Temporomandibular Joint Syndrome 2 99.56 Very High Very High Very High
Cancer 52 99.12 Very High Very High Very High
Atrial Flutter 17 98.16 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 420 94.68 High High
Arthritis 2 93.88 High High
Adhesions 3 92.76 High High
Arthralgia 1 92.00 High High
Infection 36 91.16 High High
Heart Rate Under Development 13 85.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of CN-100 on the interleukin 1-induced biosynthesis of prostaglandin E2 (PGE2) and tissue collagenase in rabbit and human rheumatoid synovial fibroblasts was also examined.
Gene_expression (biosynthesis) of interleukin 1-induced in fibroblasts
1) Confidence 0.24 Published 1990 Journal Res. Commun. Chem. Pathol. Pharmacol. Section Abstract Doc Link 2177561 Disease Relevance 0.24 Pain Relevance 0.19
The distal pole of the CS catheter is positioned at 4 to 6 o’clock in the LAO position.
Gene_expression (position) of LAO in pole
2) Confidence 0.23 Published 2006 Journal Indian Pacing and Electrophysiology Journal Section Body Doc Link PMC1501100 Disease Relevance 0.65 Pain Relevance 0
The symbols and parameters for the HOTSM reaction scheme in Fig 1 are listed below:
Gene_expression (symbols) of Fig 1
3) Confidence 0.22 Published 2004 Journal BMC Pharmacol Section Body Doc Link PMC493267 Disease Relevance 0 Pain Relevance 0.09
The most comprehensive published information about mental health in Lao PDR is a situation analysis conducted in 2002, which does not include financing [16].

Gene_expression (health) of Lao associated with mental disorders
4) Confidence 0.15 Published 2010 Journal Int J Ment Health Syst Section Body Doc Link PMC2889860 Disease Relevance 1.26 Pain Relevance 0
Lao PDR is in the border of the Golden Triangle which is one of the important sources of opium globally speaking.
Gene_expression (is) of Lao
5) Confidence 0.10 Published 2008 Journal Harm Reduct J Section Body Doc Link PMC2546385 Disease Relevance 0.42 Pain Relevance 0
Lao PDR has Myanmar, China (Yunnan), Viet Nam, Thailand and Cambodia as its neighbours and injecting drug use has been reported in all these countries.
Gene_expression (has) of Lao
6) Confidence 0.09 Published 2008 Journal Harm Reduct J Section Body Doc Link PMC2546385 Disease Relevance 0.45 Pain Relevance 0
Hyaluronate inhibits the interleukin-1beta-induced expression of matrix metalloproteinase (MMP)-1 and MMP-3 in human synovial cells.
Gene_expression (expression) of interleukin-1beta-induced in synovial cells associated with metalloproteinase
7) Confidence 0.07 Published 2004 Journal Tohoku J. Exp. Med. Section Title Doc Link 15383690 Disease Relevance 0.26 Pain Relevance 0.68
Some examples of therapeutic strategies such as gene or drug delivery systems using stem cell homing show an anti-cancer efficacy, including EGFR antagonist, IL-2, IL-4 cytotoxin, interleukin-13 receptor-directed cytotoxin [32], BMP-1/-2, IFN-?
Gene_expression (receptor) of IL-4 cytotoxin in stem cell associated with cancer and antagonist
8) Confidence 0.01 Published 2008 Journal Cancer Cell Int Section Body Doc Link PMC2474582 Disease Relevance 0.82 Pain Relevance 0.12
Role of Wnt-5A in interleukin-1beta-induced matrix metalloproteinase expression in rabbit temporomandibular joint condylar chondrocytes.
Gene_expression (expression) of interleukin-1beta-induced in temporomandibular joint associated with snapping jaw and metalloproteinase
9) Confidence 0.00 Published 2009 Journal Arthritis Rheum. Section Title Doc Link 19714632 Disease Relevance 0.10 Pain Relevance 0.28

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