INT215876

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.22
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Atf4, Hspa5) unfolded protein binding (Hspa5) endoplasmic reticulum (Hspa5)
plasma membrane (Atf4) cytoskeleton (Atf4) DNA binding (Atf4)
Anatomy Link Frequency
fibroblasts 1
Atf4 (Mus musculus)
Hspa5 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 12 72.40 Quite High
Inflammation 6 5.00 Very Low Very Low Very Low
Chronic pancreatitis 2 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Cholecystokinin 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 36 100.00 Very High Very High Very High
Death 52 94.08 High High
Obesity 3 85.84 High High
INFLAMMATION 18 72.40 Quite High
Apoptosis 28 37.92 Quite Low
Targeted Disruption 12 23.28 Low Low
Pancreatitis 22 5.00 Very Low Very Low Very Low
Frailty 22 5.00 Very Low Very Low Very Low
Diabetes Mellitus 9 5.00 Very Low Very Low Very Low
Necrosis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As ATF4 is noted to regulate ER-stress response genes such as BiP, Chop, and Xbp1-s in fibroblasts, we measured the mRNA levels of these genes in Atf4 KO and wild-type pancreata to see if this regulation holds true for this tissue (Table 1).
ATF4 Regulation (regulate) of BiP in fibroblasts associated with stress
1) Confidence 0.22 Published 2007 Journal BMC Cell Biol Section Body Doc Link PMC2072952 Disease Relevance 0.43 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox