INT215896

Context Info Confidence 0.36 First Reported 2007 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.42 Pain Relevance 0.03

transport (Slc2a1) transmembrane transporter activity (Slc2a1) plasma membrane (Slc2a1) intracellular (Slc2a1) transmembrane transport (Slc2a1) cytoplasm (Slc2a1)

Anatomy Link Frequency plasma 1 endothelial cells 1 Slc2a1 (Mus musculus)

Pain Link Frequency Relevance Heat Immobilon 1 61.20 Spinal cord 40 41.28 cytokine 17 8.56 Central nervous system 10 5.00 agonist 10 5.00 Inflammation 8 5.00 tolerance 6 5.00 anesthesia 4 5.00 Multiple sclerosis 3 5.00 ischemia 1 5.00

Disease Link Frequency Relevance Heat Motor Neuron Diseases 36 94.72 Congenital Anomalies 3 89.52 Cerebral Edema 3 66.08 Disease 47 49.60 Nerve Degeneration 6 30.60 Targeted Disruption 6 6.68 Insulin Resistance 40 5.00 Obesity 20 5.00 INFLAMMATION 9 5.00 Body Weight 9 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Glut-1 is associated mainly with the brain capillary endothelial cells and is asymmetrically distributed between the luminal and abluminal membranes [54].

Glut-1 Binding (associated) of in endothelial cells

1) Confidence 0.36 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2075163 Disease Relevance 0.42 Pain Relevance 0

Cells were submitted to subcellular fractionation for plasma membrane and internal membrane isolation before immunoblotting with GLUT4, GLUT1, and caveolin-1 antibodies (8).

GLUT1 Binding (immunoblotting) of in plasma

2) Confidence 0.18 Published 2008 Journal Diabetes Section Body Doc Link PMC2584126 Disease Relevance 0 Pain Relevance 0.03

General Comments

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