INT215901

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Context Info
Confidence 0.02
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.81
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Ins1, Igfals) extracellular space (Ins1) cell adhesion (Igfals)
nucleus (Igfals) carbohydrate metabolic process (Ins1) cytoplasm (Ins1)
Ins1 (Mus musculus)
Igfals (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 40 83.92 Quite High
Central nervous system 10 75.68 Quite High
Inflammation 4 5.00 Very Low Very Low Very Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Motor Neuron Diseases 36 100.00 Very High Very High Very High
Targeted Disruption 3 84.80 Quite High
Weight Loss 3 32.72 Quite Low
Tremor 4 32.20 Quite Low
Disease 46 31.56 Quite Low
Nerve Degeneration 6 16.96 Low Low
Death 2 15.04 Low Low
Body Weight 8 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Paralysis 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, Pirttila et al. [48] showed that insulin-like growth factor (IGF)-1, IGF binding protein-2, or nitric oxide were not elevated in CSF of ALS patients, suggesting that there is not a major disruption in the BCSFB.
insulin Neg (not) Positive_regulation (elevated) of ALS associated with motor neuron diseases
1) Confidence 0.02 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2075163 Disease Relevance 0.81 Pain Relevance 0.15

General Comments

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