INT215918

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Context Info
Confidence 0.31
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp14) cytoplasm (Mmp14)
Anatomy Link Frequency
spinal cord 2
Mmp14 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 9 99.96 Very High Very High Very High
Inflammation 6 94.24 High High
metalloproteinase 65 91.88 High High
Central nervous system 30 91.52 High High
Inflammatory mediators 1 62.64 Quite High
cytokine 10 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
glial activation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Multiple Sclerosis 51 99.72 Very High Very High Very High
Sprains And Strains 2 98.72 Very High Very High Very High
INFLAMMATION 7 94.24 High High
Targeted Disruption 17 5.00 Very Low Very Low Very Low
Injury 10 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Cancer 5 5.00 Very Low Very Low Very Low
Bordatella Infection 3 5.00 Very Low Very Low Very Low
Paralysis 3 5.00 Very Low Very Low Very Low
Mycobacterial Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We confirmed that the previously established pattern of MT-MMP regulation in EAE spinal cord: downregulation of MMP-15, 16, 17 and 24, and upregulation of MMP-14 and 25 is independent of mouse strain, myelin antigen, and use of adjuvant.
Negative_regulation (downregulation) of Positive_regulation (upregulation) of MMP-14 in spinal cord associated with multiple sclerosis, sprains and strains and spinal cord
1) Confidence 0.31 Published 2007 Journal J Neuroinflammation Section Body Doc Link PMC2075488 Disease Relevance 0.45 Pain Relevance 0.56

General Comments

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