| The indication for surgery depends on clinical symptoms of progressive renal osteopathy and impaired calcemic response following PTH secretion in the absence of Vitamin D deficiency: either if hypercalcemia develops (spontaneously or under treatment with Vitamin D), if the new therapeutic modalities fail to control sHPT or if medical therapy has to be adjourned because of adverse reactions.
| Neg (fail) Regulation (control) of sHPT associated with adverse drug reaction, hypercalcemia and bone disease
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