INT215975

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Context Info
Confidence 0.26
First Reported 2007
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.75
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

HPT (Homo sapiens)
Pain Link Frequency Relevance Heat
Cold hyperalgesia 10 99.46 Very High Very High Very High
Pain 36 92.48 High High
Thermal hyperalgesia 2 90.64 High High
Hyperalgesia 23 75.00 Quite High
Inflammation 37 60.00 Quite High
c fibre 11 50.88 Quite High
Pain threshold 33 5.00 Very Low Very Low Very Low
Quantitative sensory testing 14 5.00 Very Low Very Low Very Low
depression 5 5.00 Very Low Very Low Very Low
Neuropathic pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperalgesia 35 99.46 Very High Very High Very High
Reflex Sympathetic Dystrophy 132 98.54 Very High Very High Very High
Hypercalcemia 22 97.94 Very High Very High Very High
Adverse Drug Reaction 2 97.84 Very High Very High Very High
Recurrence 20 96.84 Very High Very High Very High
Bone Disease 10 95.56 Very High Very High Very High
Disease 21 94.60 High High
Pain 67 92.48 High High
Chronic Renal Failure 10 83.88 Quite High
Complex Regional Pain Syndromes 2 75.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The indication for surgery depends on clinical symptoms of progressive renal osteopathy and impaired calcemic response following PTH secretion in the absence of Vitamin D deficiency: either if hypercalcemia develops (spontaneously or under treatment with Vitamin D), if the new therapeutic modalities fail to control sHPT or if medical therapy has to be adjourned because of adverse reactions.
Neg (fail) Regulation (control) of sHPT associated with adverse drug reaction, hypercalcemia and bone disease
1) Confidence 0.26 Published 2007 Journal Trials Section Body Doc Link PMC2075519 Disease Relevance 0.60 Pain Relevance 0
This variation is dependent on the definition of recurrent sHPT and variability in follow up periods given in different series for both techniques [32].
Regulation (dependent) of sHPT
2) Confidence 0.19 Published 2007 Journal Trials Section Body Doc Link PMC2075519 Disease Relevance 0.67 Pain Relevance 0
In acute CRPS I, patients showed warm and cold hyperalgesia, indicated by significant changes in HPT and CPT.
Regulation (changes) of HPT associated with hyperalgesia, cold hyperalgesia and reflex sympathetic dystrophy
3) Confidence 0.11 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2453233 Disease Relevance 1.49 Pain Relevance 0.66

General Comments

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