INT216080

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Context Info
Confidence 0.31
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 2.29
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Nrtn)
Anatomy Link Frequency
dopaminergic neurons 2
Nrtn (Mus musculus)
Pain Link Frequency Relevance Heat
Substantia nigra 24 95.24 Very High Very High Very High
Dopamine 36 68.60 Quite High
palliative 4 60.84 Quite High
Nerve growth factor 16 50.56 Quite High
deep brain stimulation 4 27.36 Quite Low
Ventral tegmentum 12 5.00 Very Low Very Low Very Low
Neurotransmitter 8 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 96 98.16 Very High Very High Very High
Parkinson's Disease 12 96.76 Very High Very High Very High
Toxicity 8 93.40 High High
Stress 4 80.60 Quite High
Neurodegenerative Disease 8 70.56 Quite High
Disease Progression 4 30.52 Quite Low
Congenital Anomalies 8 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The amount of NTN mRNA and secreted NTN protein in the culture medium were detected by northern and western blots, respectively.
Localization (secreted) of NTN protein
1) Confidence 0.31 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC2082017 Disease Relevance 0.33 Pain Relevance 0.13
The amount of NTN mRNA and secreted NTN protein in the culture medium were detected by northern and western blots, respectively.
Localization (secreted) of NTN mRNA
2) Confidence 0.31 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC2082017 Disease Relevance 0.33 Pain Relevance 0.13
In our previous experiment, we transplanted an NTN-secreting c17.2 NSC line into the striatum of a 6-OHDA PD model and found that the inverse transfer of the NTN protein into the SN protected dopaminergic neurons from 6-OHDA toxicity.
Localization (-) of NTN in dopaminergic neurons associated with toxicity, substantia nigra and disease
3) Confidence 0.31 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC2082017 Disease Relevance 0.81 Pain Relevance 0.16
In our previous experiment, we transplanted an NTN-secreting c17.2 NSC line into the striatum of a 6-OHDA PD model and found that the inverse transfer of the NTN protein into the SN protected dopaminergic neurons from 6-OHDA toxicity.
Localization (secreting) of NTN in dopaminergic neurons associated with toxicity, substantia nigra and disease
4) Confidence 0.27 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC2082017 Disease Relevance 0.81 Pain Relevance 0.16

General Comments

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