INT216124
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
In addition to increased expression of Sox17 (data not shown), mRNAs for the cyclin-dependent kinase inhibitors p15, p21, and p57 were significantly decreased in lungs of CCSPrtTA/tetO-Sox17 mice relative to CCSPrtTA controls following 1 day of exposure to Dox (Fig. 5). | |||||||||||||||
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This lesion is secondary to a mononuclear decrease in cyclin–guanine monophosphate that impairs the killing of bacteria. | |||||||||||||||
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Also, Cyclin A and Cdk 6 expression levels were decreased in HPAC. | |||||||||||||||
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More recent study, however, has altered this view and revealed that even p21cip1 proteins are specific inhibitors of Cyclin E- and A-dependent Cdk2, they act as positive regulators of Cyclin D-dependent kinases.31 Thus, the increase of Cyclin D1 level in BxPC-3 cells may be the consequence of the overexpression of p21cip1. | |||||||||||||||
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General Comments
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