INT216253

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (ZNF492) intracellular (ZNF492) DNA binding (ZNF492)
ZNF492 (Homo sapiens)
ZNF492 - F1473C (1)
Pain Link Frequency Relevance Heat
potassium channel 5 93.68 High High
Mexiletine 21 91.56 High High
sodium channel 3 77.96 Quite High
Action potential 14 39.76 Quite Low
addiction 7 5.00 Very Low Very Low Very Low
lidocaine 4 5.00 Very Low Very Low Very Low
action potential duration 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 1 82.60 Quite High
Arrhythmia Under Development 2 50.16 Quite High
Disease 5 25.36 Quite Low
Syndrome 13 17.28 Low Low
Heart Rate Under Development 3 9.32 Low Low
Sudden Infant Death Syndrome 6 5.00 Very Low Very Low Very Low
Syncope 4 5.00 Very Low Very Low Very Low
Sudden Death 2 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 1 5.00 Very Low Very Low Very Low
Channelopathies 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This effect might be tolerated in treatment of adult LQT-3 mutation carriers but it might offset the effects of flecainide on F1473C mutant channel activity in the mutation carrier due to his age and genetic background.
Spec (might) Regulation (effects) of F1473C (F1473C)
1) Confidence 0.03 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2082660 Disease Relevance 0.13 Pain Relevance 0.28

General Comments

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