INT216258

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Context Info
Confidence 0.40
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.45
Pain Relevance 0.74

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nos1) mitochondrion (Nos1) oxidoreductase activity (Nos1)
plasma membrane (Nos1) cytoskeleton (Nos1) nucleus (Nos1)
Anatomy Link Frequency
dorsal horn 2
Nos1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 84 98.32 Very High Very High Very High
dorsal root ganglion 45 98.28 Very High Very High Very High
Dorsal horn 14 97.84 Very High Very High Very High
Kinase C 39 96.80 Very High Very High Very High
Spinal cord 24 86.80 High High
Glutamate 10 84.24 Quite High
nMDA receptor 1 74.16 Quite High
Calcium channel 1 70.24 Quite High
intrathecal 16 51.36 Quite High
withdrawal 15 51.04 Quite High
Disease Link Frequency Relevance Heat
Nervous System Injury 73 99.82 Very High Very High Very High
Ganglion Cysts 45 98.28 Very High Very High Very High
Targeted Disruption 19 69.44 Quite High
Hypersensitivity 30 61.92 Quite High
Pain 12 49.20 Quite Low
Neuropathic Pain 24 10.96 Low Low
Urological Neuroanatomy 18 5.00 Very Low Very Low Very Low
Nociception 9 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, L5 spinal nerve injury did not change the expression level of nNOS in either ipsilateral or contralateral L4 DRG and L4 dorsal horn at day 7 post-nerve injury (data not shown).
Neg (not) Positive_regulation (change) of Neg (not) Regulation (change) of nNOS in dorsal horn associated with dorsal root ganglion, nervous system injury and dorsal horn
1) Confidence 0.40 Published 2007 Journal Mol Pain Section Body Doc Link PMC2089056 Disease Relevance 1.45 Pain Relevance 0.50
In the postsynapse, the regulation of nNOS is dependent on the balance between activating and inactivating phosphorylation.
Positive_regulation (dependent) of Regulation (regulation) of nNOS
2) Confidence 0.34 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2890584 Disease Relevance 0 Pain Relevance 0.25

General Comments

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