INT216262

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Context Info
Confidence 0.43
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 12
Disease Relevance 2.18
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (CYGB) cytoplasm (CYGB)
Anatomy Link Frequency
cartilage 6
blood 1
CYGB (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 1 53.92 Quite High
cva 1 11.60 Low Low
Pain 11 5.00 Very Low Very Low Very Low
tolerance 11 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
depression 2 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Neurobehavioral 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Chondrosarcoma 22 99.36 Very High Very High Very High
Cancer 58 86.48 High High
Thalassemia 1 66.48 Quite High
Congenital Anomalies 5 64.64 Quite High
Fibrosis 1 53.92 Quite High
Hemolytic Anemia 1 50.32 Quite High
Splenomegaly 1 48.20 Quite Low
Anaemia 1 47.64 Quite Low
Methemoglobinemia 1 47.32 Quite Low
Thrombocytopenia 1 39.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using the "Display library-homogeneous concepts" function, only one concept remains, showing over-expression of cytoglobin in two cartilage chondrosarcoma cell types.
Gene_expression (over) of cytoglobin in cartilage associated with chondrosarcoma
1) Confidence 0.43 Published 2008 Journal BMC Bioinformatics Section Body Doc Link PMC2567996 Disease Relevance 0.27 Pain Relevance 0
One can then examine whether there is some homogeneous set of situations where the over-expression of cytoglobin is recorded.
Gene_expression (over) of cytoglobin
2) Confidence 0.43 Published 2008 Journal BMC Bioinformatics Section Body Doc Link PMC2567996 Disease Relevance 0.19 Pain Relevance 0
Similarly, formal concepts associating cytoglobin gene over-expression and cartilage-derived libraries are clustered together (Figure 4).
Gene_expression (over) of cytoglobin in cartilage
3) Confidence 0.43 Published 2008 Journal BMC Bioinformatics Section Body Doc Link PMC2567996 Disease Relevance 0 Pain Relevance 0
No over-expression of cytoglobin has been described yet in chondrosarcomas, and therefore this should be investigated further by biological means.

3.

Gene_expression (over) of cytoglobin associated with chondrosarcoma
4) Confidence 0.43 Published 2008 Journal BMC Bioinformatics Section Body Doc Link PMC2567996 Disease Relevance 0.28 Pain Relevance 0
Using the "Display library-homogeneous concepts" function, only one concept remains, showing over-expression of cytoglobin in two cartilage chondrosarcoma cell types.
Gene_expression (expression) of cytoglobin in cartilage associated with chondrosarcoma
5) Confidence 0.33 Published 2008 Journal BMC Bioinformatics Section Body Doc Link PMC2567996 Disease Relevance 0.27 Pain Relevance 0
One can then examine whether there is some homogeneous set of situations where the over-expression of cytoglobin is recorded.
Gene_expression (-) of cytoglobin
6) Confidence 0.33 Published 2008 Journal BMC Bioinformatics Section Body Doc Link PMC2567996 Disease Relevance 0.19 Pain Relevance 0
Similarly, formal concepts associating cytoglobin gene over-expression and cartilage-derived libraries are clustered together (Figure 4).
Gene_expression (-) of cytoglobin in cartilage
7) Confidence 0.33 Published 2008 Journal BMC Bioinformatics Section Body Doc Link PMC2567996 Disease Relevance 0 Pain Relevance 0
No over-expression of cytoglobin has been described yet in chondrosarcomas, and therefore this should be investigated further by biological means.

3.

Gene_expression (expression) of cytoglobin associated with chondrosarcoma
8) Confidence 0.33 Published 2008 Journal BMC Bioinformatics Section Body Doc Link PMC2567996 Disease Relevance 0.28 Pain Relevance 0
Using the "Display library-homogeneous concepts" function, only one concept remains, showing over-expression of cytoglobin in two cartilage chondrosarcoma cell types.
Gene_expression (-) of cytoglobin in cartilage associated with chondrosarcoma
9) Confidence 0.33 Published 2008 Journal BMC Bioinformatics Section Body Doc Link PMC2567996 Disease Relevance 0.27 Pain Relevance 0
Similarly, formal concepts associating cytoglobin gene over-expression and cartilage-derived libraries are clustered together (Figure 4).
Gene_expression (expression) of cytoglobin in cartilage
10) Confidence 0.33 Published 2008 Journal BMC Bioinformatics Section Body Doc Link PMC2567996 Disease Relevance 0 Pain Relevance 0
One can then examine whether there is some homogeneous set of situations where the over-expression of cytoglobin is recorded.
Gene_expression (expression) of cytoglobin
11) Confidence 0.33 Published 2008 Journal BMC Bioinformatics Section Body Doc Link PMC2567996 Disease Relevance 0.19 Pain Relevance 0
For abnormal hemoglobin levels (Hgb), significant correlations were found for number of years using pesticides (p = 0.017), not consulting a doctor when sick (p = 0,025), abnormal respiratory rate and sex, indicating that male farmers have higher abnormal Hgb level, and abnormal blood pressure (p = 0.008).
Gene_expression (levels) of Hgb in blood
12) Confidence 0.26 Published 2007 Journal J Occup Med Toxicol Section Body Doc Link PMC2089062 Disease Relevance 0.24 Pain Relevance 0.03

General Comments

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