INT216289

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Context Info
Confidence 0.48
First Reported 2001
Last Reported 2001
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.03
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (BTK) cytosol (BTK) plasma membrane (BTK)
nucleus (BTK) cytoplasm (BTK)
Anatomy Link Frequency
B cells 1
BTK (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 2 20.76 Low Low
Disease Link Frequency Relevance Heat
Disease 2 85.92 High High
Agammaglobulinemia 92 82.40 Quite High
Cytomegalovirus Infection 2 75.24 Quite High
Togavirus Infection 2 74.36 Quite High
Measles 2 73.80 Quite High
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 62.52 Quite High
Infection 12 62.40 Quite High
Liver Failure 2 57.04 Quite High
Pneumonia 8 55.60 Quite High
Bronchiectasis 2 40.92 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Measurement of the BTK protein in CD20+ B cells using anti-BTK monoclonal antibody 48-2H [5] gave an uninformative result because only a small number of CD20+ B cells were present (data not shown).
Positive_regulation (using) of anti-BTK in B cells
1) Confidence 0.48 Published 2001 Journal Respir Res Section Body Doc Link PMC2092384 Disease Relevance 0.51 Pain Relevance 0
This deletion places a stop codon just downstream, thus producing a truncated BTK protein with 604 amino acid residues instead of the normal BTK protein with 659 residues (Fig. 1C,D).
Positive_regulation (truncated) of BTK
2) Confidence 0.48 Published 2001 Journal Respir Res Section Body Doc Link PMC2092384 Disease Relevance 0.53 Pain Relevance 0

General Comments

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