INT216520

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Context Info
Confidence 0.45
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.43
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (P2ry1) mitochondrion (P2ry1) plasma membrane (P2ry1)
signal transducer activity (P2ry1)
P2ry1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 20 71.52 Quite High
antiepileptic Drug 8 60.56 Quite High
Neuronal excitability 2 54.88 Quite High
Gabapentin 1 10.32 Low Low
long-term potentiation 2 9.60 Low Low
imagery 1 5.04 Very Low Very Low Very Low
adenocard 23 5.00 Very Low Very Low Very Low
tolerance 8 5.00 Very Low Very Low Very Low
depression 7 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Epilepsy 29 88.08 High High
Partial Seizures 1 80.60 Quite High
Body Weight 11 78.24 Quite High
Impaired Glucose Tolerance 10 71.64 Quite High
Convulsion 11 44.48 Quite Low
Sclerosis 1 36.44 Quite Low
Post-traumatic Epilepsy 1 35.40 Quite Low
Keloid Scars 1 34.04 Quite Low
Disease 4 20.72 Low Low
Depression 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The P2Y1 receptor is involved in the maintenance of glucose homeostasis and in insulin secretion in mice

Pancreatic ?

Regulation (involved) of Gene_expression (receptor) of P2Y1
1) Confidence 0.45 Published 2005 Journal Purinergic Signal Section Title Doc Link PMC2096536 Disease Relevance 0.15 Pain Relevance 0
However, the gap-junction protein Cx43 has been shown to modulate both astrocytic P2Y1 receptor expression levels [74] and pharmacological function [75].
Regulation (modulate) of Gene_expression (expression) of P2Y1 receptor
2) Confidence 0.23 Published 2008 Journal Purinergic Signal Section Body Doc Link PMC2583203 Disease Relevance 0.28 Pain Relevance 0.09

General Comments

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