INT216522

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Context Info
Confidence 0.42
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (P2ry1) mitochondrion (P2ry1) plasma membrane (P2ry1)
signal transducer activity (P2ry1)
P2ry1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 8 71.36 Quite High
agonist 3 26.24 Quite Low
withdrawal 1 5.00 Very Low Very Low Very Low
adenocard 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Impaired Glucose Tolerance 10 69.88 Quite High
Insulin Resistance 4 57.92 Quite High
Body Weight 11 45.96 Quite Low
Obesity 3 5.00 Very Low Very Low Very Low
Thrombosis 2 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low
Hyperinsulinism 1 5.00 Very Low Very Low Very Low
Hyperglycemia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-cell function is improved in P2Y1-deficient mice, particularly in the presence of high glucose concentrations, pointing to a putative inhibitory effect of the P2Y1 receptor on insulin secretion.
Negative_regulation (effect) of Localization (secretion) of P2Y1
1) Confidence 0.42 Published 2005 Journal Purinergic Signal Section Body Doc Link PMC2096536 Disease Relevance 0.13 Pain Relevance 0.07

General Comments

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