INT216545

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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Kcnma1) enzyme binding (Cftr) protein complex (Cftr)
transmembrane transport (Cftr) cytoplasm (Cftr) ATPase activity (Cftr)
Anatomy Link Frequency
CPAE 2
Cftr (Rattus norvegicus)
Kcnma1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
fluoxetine 1 55.88 Quite High
ischemia 6 5.00 Very Low Very Low Very Low
fibrosis 5 5.00 Very Low Very Low Very Low
addiction 5 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
Bile 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
agonist 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pressure And Volume Under Development 27 96.48 Very High Very High Very High
Hypoxia 8 5.00 Very Low Very Low Very Low
Stress 8 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 6 5.00 Very Low Very Low Very Low
Cystic Fibrosis 5 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Pheochromocytoma 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Heterologous expression of CFTR was shown to downregulate VSOR anion channel activity in CPAE and COS cells [116] as well as in HEK293T cells [117], but upregulate swelling-induced ATP release from C127/CFTR cells [58, 60].
Gene_expression (expression) of CFTR in CPAE Negative_regulation (downregulate) of channel associated with pressure and volume under development
1) Confidence 0.00 Published 2005 Journal Purinergic Signal Section Body Doc Link PMC2096548 Disease Relevance 0.59 Pain Relevance 0.06

General Comments

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