INT216668

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Context Info
Confidence 0.00
First Reported 2004
Last Reported 2004
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (NLRP1, Vta1) cytosol (NLRP1) nucleus (NLRP1)
intracellular (NLRP1) enzyme binding (NLRP1)
NLRP1 (Homo sapiens)
Vta1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 63 100.00 Very High Very High Very High
Nucleus accumbens 32 100.00 Very High Very High Very High
Ventral tegmentum 18 100.00 Very High Very High Very High
agonist 9 99.90 Very High Very High Very High
antagonist 21 29.28 Quite Low
cocaine 1 23.68 Low Low
adenocard 21 8.80 Low Low
Glutamate 21 5.00 Very Low Very Low Very Low
Eae 9 5.00 Very Low Very Low Very Low
GABAergic 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 3 5.00 Very Low Very Low Very Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low
Starvation 2 5.00 Very Low Very Low Very Low
Eating Disorder 2 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low
Bordatella Infection 1 5.00 Very Low Very Low Very Low
Hypersensitivity 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low
Appetite Loss 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, P2 receptor agonists may modulate the activity of dopaminergic cell bodies in the VTA both by local direct stimulation and/or indirect inhibitory control via dopamine release and subsequent dopamine D2 receptor stimulation in the NAc.
Positive_regulation (stimulation) of NAc Spec (may) Regulation (modulate) of VTA associated with nucleus accumbens, ventral tegmentum, dopamine and agonist
1) Confidence 0.00 Published 2004 Journal Purinergic Signal Section Body Doc Link PMC2096569 Disease Relevance 0 Pain Relevance 0.73

General Comments

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