INT216670

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Context Info
Confidence 0.35
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.54
Pain Relevance 1.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Postn) cell adhesion (Postn) proteinaceous extracellular matrix (Postn)
extracellular matrix organization (Postn)
Anatomy Link Frequency
upper 1
neutrophil 1
Postn (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 111 100.00 Very High Very High Very High
Pain 61 99.98 Very High Very High Very High
Morphine 61 98.68 Very High Very High Very High
Mcgill questionnaire 4 83.40 Quite High
Analgesic 11 79.16 Quite High
peripheral neuropathy 6 76.72 Quite High
Opioid 19 55.68 Quite High
Inflammation 10 54.24 Quite High
Inflammatory mediators 1 51.20 Quite High
Neuropathic pain 11 50.00 Quite Low
Disease Link Frequency Relevance Heat
Pain 73 99.98 Very High Very High Very High
Injury 45 93.32 High High
Urological Neuroanatomy 14 90.04 High High
Peripheral Neuropathy 12 76.72 Quite High
Wound Healing 2 71.16 Quite High
Infection 7 69.96 Quite High
Nociception 26 62.36 Quite High
INFLAMMATION 12 54.24 Quite High
Stress 32 50.00 Quite Low
Neuropathic Pain 23 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Elastic bands of 0.5 mm thickness were inserted between the first and second upper molars of the wild-type mice and littermates homozygous for periostin gene depletion and left there for 3 days.
Negative_regulation (depletion) of periostin in upper
1) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923609 Disease Relevance 0 Pain Relevance 0
Pain reduction effects of Neuragen PN® and the placebo were measured using the VAS 30 minutes before (Pre) and after (Post) treatment application.
Negative_regulation (reduction) of Neuragen PN associated with pain
2) Confidence 0.09 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC2883533 Disease Relevance 0.67 Pain Relevance 0.68
However, with the exception of KC levels, peri-incisional cytokine levels were reduced by the 100-fold lower 0.1 mg/kg morphine dose, a dose at which neutrophil infiltration was unaffected.
Negative_regulation (reduced) of peri-incisional in neutrophil associated with morphine and cytokine
3) Confidence 0.02 Published 2007 Journal Mol Pain Section Body Doc Link PMC2096620 Disease Relevance 0.87 Pain Relevance 1.22

General Comments

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