INT216736

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Context Info
Confidence 0.08
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.06
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ADORA2B, ATP6V0A1) Golgi apparatus (ATP6V0A1) nucleolus (ATP6V0A1)
nucleus (ATP6V0A1) transmembrane transport (ATP6V0A1) cytoplasm (ATP6V0A1)
ADORA2B (Homo sapiens)
ATP6V0A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 171 100.00 Very High Very High Very High
antagonist 71 99.96 Very High Very High Very High
agonist 46 72.96 Quite High
Potency 2 27.32 Quite Low
Pain 1 13.24 Low Low
Inflammation 5 10.08 Low Low
Analgesic 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 5 55.04 Quite High
Pain 1 13.24 Low Low
Cv Unclassified Under Development 1 12.88 Low Low
Injury 1 12.44 Low Low
Cancer 2 11.56 Low Low
Asthma 6 11.24 Low Low
INFLAMMATION 6 10.08 Low Low
Breast Cancer 1 5.28 Low Low
Neuroblastoma 4 5.00 Very Low Very Low Very Low
Glioma 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Xanthines, including the natural derivatives theophylline and caffeine, are the natural non-selective antagonists of adenosine and they are able to bind to all four adenosine receptor subtypes A1, A2A, A2B and A3 [6].
A2B Binding (bind) of A1 associated with adenocard and antagonist
1) Confidence 0.08 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2096665 Disease Relevance 0 Pain Relevance 0.52
We tried to displace the A1 selective radioligand [3H]CHA with increasing concentrations of the adenosine A2B receptor antagonists.
adenosine A2B receptor Binding (radioligand) of A1 associated with adenocard and antagonist
2) Confidence 0.04 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2096648 Disease Relevance 0.06 Pain Relevance 0.41

General Comments

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