INT216785

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Context Info
Confidence 0.03
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.05
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (P2ry12) extracellular space (Svs4) extracellular region (Svs4)
plasma membrane (P2ry12) signal transducer activity (P2ry12)
Anatomy Link Frequency
microglia 2
Svs4 (Rattus norvegicus)
P2ry12 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 9 50.00 Quite Low
adenocard 10 44.72 Quite Low
antagonist 4 37.72 Quite Low
Inflammation 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
addiction 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bordatella Infection 3 52.16 Quite High
INFLAMMATION 8 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Nervous System Injury 1 5.00 Very Low Very Low Very Low
Necrosis 1 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 1 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Chronic Disease 1 5.00 Very Low Very Low Very Low
Stress 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Involvement of PTx-sensitive Gi in the mechanism leading to Ca2+ rise by ADP further supports the idea that activation of P2Y12 receptors is responsible for ADP-induced Ca2+ movements in microglia.
ADP Regulation (responsible) of Positive_regulation (activation) of P2Y12 in microglia
1) Confidence 0.03 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2096653 Disease Relevance 0.05 Pain Relevance 0

General Comments

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