INT216841

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Context Info
Confidence 0.01
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TCIRG1, ADCY1) transmembrane transport (TCIRG1, ADCY1) signal transduction (ADCY1)
mitochondrion (TCIRG1) small molecule metabolic process (ADCY1) nucleus (ADCY1)
TCIRG1 (Homo sapiens)
ADCY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 27 87.96 High High
Inflammation 5 69.12 Quite High
antagonist 24 50.00 Quite Low
agonist 14 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Asthma 5 72.72 Quite High
Neurodegenerative Disease 1 72.08 Quite High
INFLAMMATION 5 69.12 Quite High
Disease 2 68.08 Quite High
Cancer 2 67.04 Quite High
Hypoxia 1 28.96 Quite Low
Diabetic Retinopathy 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Breast Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In particular A1 and A3 inhibit, through Gi proteins, adenylyl cyclase activity, whereas A2A and A2B stimulate, via Gs proteins, this enzyme.
A3 Negative_regulation (inhibit) of adenylyl cyclase
1) Confidence 0.01 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2096665 Disease Relevance 0.35 Pain Relevance 0.18

General Comments

This test has worked.

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