INT216889

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Context Info
Confidence 0.23
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (P2rx7) cell morphogenesis (P2rx7) mitochondrion organization (P2rx7)
protein complex (P2rx7) transmembrane transport (P2rx7) cytoplasm (P2rx7)
P2rx7 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 6 99.04 Very High Very High Very High
cytokine 9 84.48 Quite High
antagonist 2 81.80 Quite High
adenocard 43 41.04 Quite Low
Inflammation 8 5.00 Very Low Very Low Very Low
ischemia 7 5.00 Very Low Very Low Very Low
Nerve growth factor 5 5.00 Very Low Very Low Very Low
Endocannabinoid 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 4 5.00 Very Low Very Low Very Low
Neuropathic pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 14 46.08 Quite Low
Middle Cerebral Artery Infarction 5 35.96 Quite Low
Alzheimer's Dementia 2 5.60 Low Low
Disease 16 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 7 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Sclerosis 5 5.00 Very Low Very Low Very Low
Multiple Sclerosis 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The molecular mechanism underlying the priming effect of ATP could be a reversible conformational change leading to the modification of the agonist binding motif, or the gating properties of the P2X7 receptor, or its activity-dependent phosphorylation.
Phosphorylation (phosphorylation) of P2X7 receptor associated with agonist
1) Confidence 0.23 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2096753 Disease Relevance 0 Pain Relevance 0.18

General Comments

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