INT216911

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Context Info
Confidence 0.02
First Reported 2006
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (P2rx7) cell morphogenesis (P2rx7) mitochondrion organization (P2rx7)
protein complex (P2rx7) transmembrane transport (P2rx7) cytoplasm (P2rx7)
Anatomy Link Frequency
microglia 3
P2rx7 (Mus musculus)
Plg (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 6 100.00 Very High Very High Very High
Endocannabinoid 4 96.84 Very High Very High Very High
Inflammatory mediators 4 75.84 Quite High
cytokine 9 48.36 Quite Low
Inflammation 8 48.00 Quite Low
adenocard 43 5.00 Very Low Very Low Very Low
ischemia 7 5.00 Very Low Very Low Very Low
Nerve growth factor 5 5.00 Very Low Very Low Very Low
Neuropathic pain 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 14 75.84 Quite High
Disease 16 53.48 Quite High
Alzheimer's Dementia 2 42.56 Quite Low
Apoptosis 6 9.44 Low Low
Cv Unclassified Under Development 7 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low
Middle Cerebral Artery Infarction 5 5.00 Very Low Very Low Very Low
Sclerosis 5 5.00 Very Low Very Low Very Low
Multiple Sclerosis 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, activation of P2X7 receptors by low concentration of agonists stimulates the release of the neuroprotective mediator plasminogen from cultured microglia [74].
Positive_regulation (activation) of P2X7 in microglia Positive_regulation (stimulates) of Localization (release) of plasminogen in microglia associated with agonist
1) Confidence 0.02 Published 2006 Journal Purinergic Signal Section Body Doc Link PMC2096753 Disease Relevance 0.13 Pain Relevance 0.23

General Comments

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