INT216919

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Context Info
Confidence 0.18
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ngf) extracellular space (Ngf) aging (Ngf)
extracellular region (Ngf) Golgi apparatus (P2rx3) molecular_function (Ngf)
Anatomy Link Frequency
neurons 2
Ngf (Rattus norvegicus)
P2rx3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 9 88.80 High High
bradykinin 1 88.40 High High
substance P 1 85.04 High High
Inflammatory mediators 1 76.20 Quite High
Neuropathic pain 34 72.40 Quite High
Peripheral nerve injury 6 71.04 Quite High
Stimulus evoked pain 5 65.80 Quite High
allodynia 17 51.40 Quite High
Dorsal horn 12 49.68 Quite Low
Sciatic nerve 3 40.56 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 10 88.80 High High
Neuropathic Pain 72 72.40 Quite High
Nervous System Injury 38 70.16 Quite High
Hypersensitivity 8 65.80 Quite High
Inflammatory Pain 10 65.12 Quite High
Pain 35 5.00 Very Low Very Low Very Low
Hyperalgesia 7 5.00 Very Low Very Low Very Low
Injury 5 5.00 Very Low Very Low Very Low
Infection 3 5.00 Very Low Very Low Very Low
Diabetes Mellitus 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, NGF also increases the expression of P2X3 in DRG neurons and induces new expression in some DRG neurons.
NGF Positive_regulation (increases) of Gene_expression (expression) of P2X3 in neurons
1) Confidence 0.18 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2096756 Disease Relevance 0.69 Pain Relevance 0.53

General Comments

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