INT216942

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Context Info
Confidence 0.14
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein complex (P2rx7, Casp1) cytoplasm (P2rx7, Casp1) cell death (P2rx7, Casp1)
transport (P2rx7) cell morphogenesis (P2rx7) intracellular (Casp1)
P2rx7 (Mus musculus)
Casp1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 16 50.00 Quite Low
Inflammatory response 6 49.76 Quite Low
Eae 2 32.16 Quite Low
antagonist 6 22.32 Low Low
Inflammatory mediators 6 17.36 Low Low
Inflammation 35 5.00 Very Low Very Low Very Low
cytokine 22 5.00 Very Low Very Low Very Low
Neuropathic pain 7 5.00 Very Low Very Low Very Low
Arthritis 4 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 16 50.00 Quite Low
INFLAMMATION 48 49.76 Quite Low
Neuropathic Pain 14 33.44 Quite Low
Inflammatory Pain 1 32.16 Quite Low
Targeted Disruption 8 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low
Arthritis 5 5.00 Very Low Very Low Very Low
Hypersensitivity 4 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Uniquely in this receptor family, activation of P2X7 can also activate caspase 1, which causes rapid release of mature, biologically active interleukin-1?
Positive_regulation (activation) of P2X7 Positive_regulation (activate) of caspase 1
1) Confidence 0.14 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2096758 Disease Relevance 0 Pain Relevance 0

General Comments

This test has worked.

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