INT217010

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Context Info
Confidence 0.69
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 1.31
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (P2RY2) aging (P2RY2) plasma membrane (P2RY2)
embryo development (P2RY2) lysosome (P2RY2) signal transducer activity (P2RY2)
Anatomy Link Frequency
monocytes 1
dendritic cells 1
P2RY2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 136 93.80 High High
Inflammation 44 61.72 Quite High
anesthesia 6 56.56 Quite High
psoriasis 2 49.72 Quite Low
chemokine 8 48.72 Quite Low
rheumatoid arthritis 12 36.72 Quite Low
antagonist 31 34.92 Quite Low
agonist 33 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 134 94.84 High High
Disease 24 86.28 High High
Wound Healing 69 78.72 Quite High
INFLAMMATION 44 61.72 Quite High
Psoriasis 2 49.72 Quite Low
Syndrome 2 44.40 Quite Low
Infection 8 41.44 Quite Low
Rheumatoid Arthritis 12 36.72 Quite Low
Pneumonia 2 32.48 Quite Low
Cancer 4 30.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The level of P2Y2-R mRNA was normalized to the housekeeping gene, HPRT1 (HPRT1-specific forward, 5?
Transcription (level) of P2Y2-R
1) Confidence 0.69 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2695252 Disease Relevance 0.25 Pain Relevance 0.06
The first round of PCR was performed with a rabbit P2Y2-R specific reverse primer (5?
Transcription (primer) of P2Y2-R
2) Confidence 0.60 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2695252 Disease Relevance 0 Pain Relevance 0
As shown in Figure 3, significant P2Y2-R mRNA knockdown was observed after 48 and 72 h of the first instillation (23.00%±5.65% and 10.36%±4.47% of P2Y2-R mRNA remaining, respectively; p<0.001).
Transcription (observed) of P2Y2-R
3) Confidence 0.53 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2695252 Disease Relevance 0.80 Pain Relevance 0
Human monocyte-derived dendritic cells are reported to express mRNA for P2Y1, P2Y2, P2Y4, P2Y5, P2Y6, P2Y10, P2Y11, and P2Y13 from the P2Y receptor side of the family and P2X1, P2X4, P2X5, and P2X7 from the P2X receptor lineage [37–39].
Transcription (express) of P2Y2 in dendritic cells
4) Confidence 0.23 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2096759 Disease Relevance 0 Pain Relevance 0.12
Human monocytes, for example, express mRNA encoding P2Y1, P2Y2, P2Y4, P2Y6, P2X1 and P2X7 receptors [14–16].
Transcription (express) of P2Y2 in monocytes
5) Confidence 0.22 Published 2007 Journal Purinergic Signal Section Body Doc Link PMC2096759 Disease Relevance 0.26 Pain Relevance 0.24

General Comments

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