INT217104

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Context Info
Confidence 0.28
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.46
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Rrm2) oxidoreductase activity (Rrm2) cytoplasm (Rrm2)
Anatomy Link Frequency
respiratory 1
Rrm2 (Mus musculus)
Pain Link Frequency Relevance Heat
narcan 7 53.60 Quite High
medulla 4 5.00 Very Low Very Low Very Low
Locus ceruleus 3 5.00 Very Low Very Low Very Low
parabrachial 3 5.00 Very Low Very Low Very Low
fifth nerve 2 5.00 Very Low Very Low Very Low
psoriasis 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Arthritis 2 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 54 98.84 Very High Very High Very High
Cancer 6 97.48 Very High Very High Very High
Pathologic Neovascularization 4 96.88 Very High Very High Very High
Acute Liver Failure 44 83.28 Quite High
Pathologic Processes 4 56.44 Quite High
Apnoea 17 51.44 Quite High
Disease 2 46.96 Quite Low
Wound Healing 2 42.60 Quite Low
Congenital Anomalies 5 18.80 Low Low
Injury 8 16.16 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the present study, we found that either inhibition of R1 or R2 significantly augmented the SEC destruction, and that treatment with R2-mAb was more potent than that with R1-mAb.
Negative_regulation (inhibition) of R2
1) Confidence 0.28 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2933582 Disease Relevance 0.54 Pain Relevance 0
Hoxa2 inactivation, affecting the r1-r2 region and respiratory amplitude, did not severely perturb respiratory rhythm that requires normal Krox20 and Hoxa1 expression in the r3-r5 region [26].
Negative_regulation (inactivation) of r2 in respiratory
2) Confidence 0.26 Published 2007 Journal Neural Develop Section Body Doc Link PMC2098766 Disease Relevance 0.05 Pain Relevance 0.03
Similar to the in-vivo studies, we found that inhibition of either R1-mAb or R2-mAb significantly augmented the apoptosis.
Negative_regulation (inhibition) of R2-mAb associated with apoptosis
3) Confidence 0.24 Published 2010 Journal J Angiogenes Res Section Body Doc Link PMC2933582 Disease Relevance 0.87 Pain Relevance 0

General Comments

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