INT217109

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Context Info
Confidence 0.56
First Reported 2007
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hoxa2, Egr2) DNA binding (Hoxa2, Egr2) intracellular (Egr2)
ligase activity (Egr2) cytoplasm (Egr2)
Anatomy Link Frequency
respiratory 1
Hoxa2 (Mus musculus)
Egr2 (Mus musculus)
Pain Link Frequency Relevance Heat
narcan 7 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
Locus ceruleus 3 5.00 Very Low Very Low Very Low
parabrachial 3 5.00 Very Low Very Low Very Low
fifth nerve 2 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neurodegenerative Disease 3 85.64 High High
Congenital Anomalies 5 83.12 Quite High
Apnoea 17 71.20 Quite High
Targeted Disruption 7 39.48 Quite Low
Death 2 11.84 Low Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Birth Weight 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Body Weight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these results establish that Hoxa2 does not mediate the Krox20 null respiratory phenotype in r3 since Hoxa2 null mutation does not reproduce Krox20 null mutation phenotypic traits.
Hoxa2 Neg (not) Positive_regulation (mediate) of Krox20 in respiratory
1) Confidence 0.56 Published 2007 Journal Neural Develop Section Body Doc Link PMC2098766 Disease Relevance 0.43 Pain Relevance 0

General Comments

This test has worked.

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