INT217112

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Context Info
Confidence 0.69
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Egr2, Hoxa2) DNA binding (Egr2, Hoxa2) intracellular (Egr2)
ligase activity (Egr2) cytoplasm (Egr2)
Anatomy Link Frequency
jaw 1
neural 1
Egr2 (Mus musculus)
Hoxa2 (Mus musculus)
Pain Link Frequency Relevance Heat
narcan 14 42.96 Quite Low
medulla 8 5.00 Very Low Very Low Very Low
Locus ceruleus 6 5.00 Very Low Very Low Very Low
parabrachial 6 5.00 Very Low Very Low Very Low
fifth nerve 4 5.00 Very Low Very Low Very Low
Opioid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apnoea 34 5.00 Very Low Very Low Very Low
Targeted Disruption 14 5.00 Very Low Very Low Very Low
Congenital Anomalies 10 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 6 5.00 Very Low Very Low Very Low
Sprains And Strains 4 5.00 Very Low Very Low Very Low
Birth Weight 4 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that inactivation of either Hoxa2 or Krox20 impairs the rhythmic control of the jaw opening in agreement with HOXA2-dependent trigeminal defects and direct regulation of Hoxa2 by KROX20 in r3.
KROX20 Regulation (regulation) of Hoxa2 in jaw
1) Confidence 0.69 Published 2007 Journal Neural Develop Section Body Doc Link PMC2098766 Disease Relevance 0 Pain Relevance 0
We investigated the impact of such mutations on the neural circuits controlling jaw opening and breathing in newborn mice, compatible with Hoxa2-dependent trigeminal defects and direct regulation of Hoxa2 by Krox20 in r3.


Krox20 Regulation (regulation) of Hoxa2 in neural
2) Confidence 0.30 Published 2007 Journal Neural Develop Section Abstract Doc Link PMC2098766 Disease Relevance 0 Pain Relevance 0

General Comments

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