INT217124

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.08
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.78
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Mirlet7a-1)
Mirlet7a-1 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 69 90.00 High High
Inflammation 12 73.76 Quite High
Kinase C 2 13.72 Low Low
Osteoarthritis 25 5.20 Low Low
cytokine 6 5.00 Very Low Very Low Very Low
Chronic pancreatitis 4 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Multiple sclerosis 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 14 98.28 Very High Very High Very High
Malignant Neoplastic Disease 10 96.84 Very High Very High Very High
Rheumatoid Arthritis 69 90.00 High High
Acute Promyelocytic Leukemia 4 88.68 High High
Cancer 103 84.32 Quite High
Lung Cancer 27 82.00 Quite High
Neurofibromatosis 2 2 78.64 Quite High
INFLAMMATION 13 73.76 Quite High
Arthritis 2 63.36 Quite High
Adenocarcinoma 6 59.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Meng et al. demonstrated that let-7a miRNA was upregulated and contributed to the survival effects of enforced Interleukin-6 activity in malignant human cholangiocytes.
Positive_regulation (upregulated) of let-7a associated with malignant neoplastic disease
1) Confidence 0.08 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2098778 Disease Relevance 0.72 Pain Relevance 0
Besides, ATRA downregulation of Ras and Bcl2 was shown to correlate with the activation of let-7a miRNA [12].
Positive_regulation (activation) of let-7a
2) Confidence 0.08 Published 2007 Journal Mol Cancer Section Body Doc Link PMC2098778 Disease Relevance 0.56 Pain Relevance 0
This demonstrated that let-7a, miR-26a, 146a,b, 150, and 155 were significantly upregulated in the differentiation of IL-17 producing cells.
Positive_regulation (upregulated) of let-7a
3) Confidence 0.07 Published 2010 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2950393 Disease Relevance 0.50 Pain Relevance 0.16

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox